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New Mylan-Clobetasol Scalp Treatment 60 mL bed set knife edgeNew Mylan Clobetasol Scalp Treatment 60 mL Clobetasol is a topical (skin applied) corticosteroid medication used to treat skin conditions that have not responded well to other corticosteroids, including moderate to severe psoriasis and eczematous dermatitis. The scalp lotion and shampoo are used to treat psoriasis and seborrheic dermatitis occurring on the scalp. Clobetasol works by reducing swelling, redness, and itching.